• Inspire Plays Pivotal Role In Search For Super-Genes

    Clinical Research News | The pilot project of a new HealthJourney program being developed by healthcare social network Inspire is all-virtual recruitment for a clinical research study being conducted in partnership with Pfizer, the Manton Center for Orphan Disease Research at Boston Children’s Hospital (BCH), and Citizen Genetics. The study is endeavoring to identify people in families with a history of autoimmune disease who carry “super-genes,” variants that make them resilient to lung cancer progression

    Feb 9, 2021
  • COVID-19 And Cancer: An Unsettling Pairing

    Clinical Research News | The pandemic has had potentially far-reaching effects on the treatment of cancer patients and conduct of oncology clinical trials, according to panelists presenting at last week’s COVID-19 and Cancer virtual meeting of the American Association for Cancer Research. While the medical community seems to favor extending “interim” policies related to telehealth and study enrollment, it also worries about the unintended consequences of institutional safety precautions—notably, delays in patients getting needed care.

    Feb 8, 2021
  • Asymptomatic Infections Rising, Maternal Antibody Protection, Opaganib Shows Promising Results: COVID-19 Updates

    Clinical Research News I Social distancing benefits the individual and community, airborne transmission contributed significantly to cruise ship outbreak, viral load likely peaks at symptom onset, Plus: NIH funds study to identify risk factors for severe COVID-19 in children and BioNTech-Pfizer’s COVID-19 vaccine largely effective against B.1.1.7 variant.

    Feb 5, 2021
  • Trial Design For Medical Devices: Regulatory Challenges, Opportunities

    Clinical Research News | On behalf of Clinical Research News, Bridget Kotelly spoke with Teri Takle-Flach of Boston Scientific about the biggest challenges planning clinical studies today and the impact EU Medical Device Regulation.

    Feb 3, 2021
  • AI-Based Approach Crunches Real-World Data To Emulate Clinical Trials

    Clinical Research News | A computer scientist at The Ohio State University (OSU) recently demonstrated the potential of artificial intelligence to crunch real-world data and emulate randomized clinical trials, speeding the pace of drug repurposing.

    Feb 2, 2021
  • 23andMe Launches Severity Calculator, Middle-Aged Adults Also at Danger, High Omega-3 Index Reduces Mortality Risk: COVID-19 Updates

    Clinical Research News I Cluster randomized trials could help children return safely to schools, early anticoagulation therapy does not improve outcomes, recovered patients experience lasting effects. Plus: NIH launches database to track COVID-19 related neurological symptoms and 86% of doctors believe mental health, depression will be biggest non-COVID-19 public health issue.

    Jan 29, 2021
  • New DTRA Members, Veeva Now A Public Benefit Corporation, More

    Clinical Research News | Strategic collaborations to enable more diverse trial populations, advance combinatorial intravesical immunotherapy, and engage patients in a privacy-centric way. Plus: new partnership program for CROs and an Oracle integration for Cognizant’s Shared Investigator Platform.

    Jan 28, 2021
  • Risk Management During A Pandemic: How Pfizer’s Quality Management System Fared

    Clinical Research News | Nothing quite tests a risk-based management approach like a global pandemic that few predicted. And for Pfizer’s Melissa Suprin, the COVID-19 pandemic was the first big test of the quality management system.

    Jan 26, 2021
  • Five Variants of Disease, When Patient Stratification Scores Fail, Studies for Long COVID: COVID-19 Updates

    Clinical Research News| The UK’s patient stratification score doesn’t hold up to scrutiny, Fauci and others encourage doctors to equip themselves to argue for vaccines, NIH launches a study of “Long COVID”, and more. Plus: Siemens, with German funding, sets up more COVID-19 treatment facilities for South Africa.

    Jan 22, 2021
  • Drugs Targeting Cellular Aging May Prove Useful For Numerous Conditions

    Clinical Research News | Fundamental aging processes appear to be root-cause contributors to multiple conditions, ranging from heart attacks and cancer to neurodegenerative disorders like Alzheimer’s disease. Now a series of clinical trials will look at whether senolytics— drugs targeting cellular aging—could affect many or perhaps all other aging mechanisms because they are interlinked.

    Jan 21, 2021