Get the whole story: combine Tm and Tagg with sizing and polydispersity on Uncle
Thermal ramp stability measurements (Tm and Tagg) are well-established methods for ranking proteins and formulations for stability. This data is critical for stability determinations, and ensures that researchers are focusing on winning constructs and formulations. While valuable, there is additional information that is not easily gleaned from single-mode instruments. DLS data from Uncle provides even more data on the same set of samples to fill in the missing pieces.