Press Releases

Profacgen Updated Its Electrophoretic Mobility Shift Assay (EMSA) Service

Oct 24, 2023, 08:32 AM by

Profacgen, a leading provider of life science research services, today announced the update of its Electrophoretic Mobility Shift Assay (EMSA) service, providing a powerful technique for studying protein-nucleic acid interactions.

 

Electrophoretic Mobility Shift Assay (EMSA), also known as gel shift assay, gel mobility shift assay, band shift assay, or gel retardation assay, is a common affinity electrophoresis technique used to study protein–DNA or protein–RNA interactions. This procedure can determine if a protein or mixture of proteins is capable of binding to a given DNA or RNA sequence, and can sometimes indicate if more than one protein molecule is involved in the binding complex.

 

EMSA can be used to study a wide range of protein–nucleic acid interactions, including:

  • Transcription factor binding to DNA
  • RNA binding proteins binding to RNA
  • Protein-DNA interactions in gene regulation
  • Protein-RNA interactions in microRNA processing
  • Protein-DNA interactions in DNA repair

 

Profacgen has a well-developed platform for EMSA experiments and a wealth of knowledge in nucleotide-protein binding analysis. Before beginning each project, scientists at Profacgen rigorously inspect nucleotides and proteins to make sure they are eligible for EMSA. To label nucleotides, Profacgen can use radioactive isotopes as well as other labeling substances like biotin and FAM. In order to eliminate non-specific nucleotide-protein interactions, unlabeled nucleotides are used as specific competitors. Additionally, Profacgen has cutting-edge signal detection equipment that guarantees results with a high sensitivity and signal-to-noise ratio.

 

Profacgen's service offers a number of advantages, including:

  • High sensitivity: highly sensitive detection method, allowing for the detection of even weak protein-nucleic acid interactions.
  • Fast turnaround time: optimized workflow to provide fast turnaround time for EMSA experiment.
  • Competitive pricing: competitively priced, making it accessible to researchers of all budget levels.

 

"We are excited to update our EMSA service to the science community, and we are committed to providing our customers with the highest quality services and support. We are confident that our EMSA service will be a valuable tool for researchers who need to study protein-nucleic acid interactions." Said Crystal, the chief marketing staff at Profacgen.

 

To know more detailed information about the Electrophoretic Mobility Shift Assay (EMSA) Service provided by Profacgen, please visit https://www.profacgen.com/Electrophoretic-Mobility-Shift-Assay-EMSA-Service.htm.