MUNICH, GERMANY - Jul 7, 2015 - Definiens, the global leader in image analysis for digital pathology and diagnostics, today announced the launch of Tissue Studio® 4.1. With the new release, Definiens provides faster throughput for tissue image analysis so scientists in academic medical centers, comprehensive cancer centers, and biotech and pharmaceutical companies can reach conclusions to their research questions quickly. In addition to faster throughput, Tissue Studio® 4.1 features powerful machine learning and the ability to automate routine image analysis tasks, enabling researchers to develop a customized image analysis solution in as little as twenty minutes, and reduce preclinical safety and toxicity study lengths from weeks to just days.

“Researchers have a need to obtain the best data for basic discovery and research as quickly as possible,” said Merrilyn Datta, President, Definiens. “In addition to Definiens’ biomarker and clinical development services, Tissue Studio® 4.1 provides scientists with an out-of-the-box solution that enables comprehensive and consistent data from any tissue-based assay and can handle complex tasks such as biological heterogeneity and staining variation; with Tissue Studio® 4.1, the software now provides this information even faster.”

Image analysis enables researchers to automate tedious manual analysis, produces quantitative readouts that can be mined and correlated, and simplifies analysis tasks and workflows. Adding to these standard benefits, Tissue Studio® uniquely overcomes inherent biological and staining variability to accurately detect regions of interest and distinguish cell types and cell subtypes within target regions across any number of tissue slides. Tissue Studio® 4.1 brings powerful speed and efficiency improvements to the solution of choice for image analysis in research and drug discovery on tissue samples.

Tissue Studio® 4.1 provides researchers with significant productivity gains, flexibility and ease of use. Specific benefits include:

·      Updated Processing Workflow and Faster Throughput: Facilitates two-fold faster image analysis compared to previous Tissue Studio® versions, enabling researchers to analyze significantly more slides per day. This improvement in processing speed will provide Tissue Studio® users with the ability to double their throughput in order to meet aggressive deadlines for research grants, publication review or project report-outs. An example comparison in throughput speed with Tissue Studio® 4.1 can be seen in the attached graphic.

·      Dual Stain Support:  Enables researchers to answer complex questions with fewer slides using single and dual stain with any chromogen for ISH and vessel staining, in addition to IHC. The ability to analyze dual staining is important for several indications such as immunotherapy research, oncology and diabetes, where the utilization of multiple stains on one sample is commonly utilized.

·      Automatic Alignment and Analysis of Regions on Tissue Images:  Enables researchers to automatically transfer regions selected on one stain to co-registered consecutive slides from one sample block. This allows for faster throughput and more accurate results for data analysis within regions and is of particular value when analyzing immune response and the tumor microenvironment.

Tissue Studio® 4.1 provides research labs with future-proof performance and scalability, and accurate and consistent results in research projects utilizing tissue. Most importantly, researchers can analyze tissue and obtain results faster, enabling them to complete research projects more quickly.

Current Tissue Studio® users can download the Tissue Studio® 4.1 release by contacting support@definiens.com.

Learn more about Definiens’ Tissue Studio® at www.definiens.com.

About Definiens

Definiens is the leading provider of image analysis and data mining solutions for diagnostics and clinical digital pathology. Definiens technology provides detailed cell-by-cell readouts from target structures on tissue slides and allows the correlation of this information with data derived from other sources, generating new knowledge and supporting better decisions in research, diagnostics and therapy. Definiens' Tissue Phenomics approach was awarded the 2013 Frost and Sullivan Company of the Year Award for Global Tissue Diagnostics and Pathology Imaging. For more information, please visit: www.definiens.com.